dihydroceramide desaturase (Des1) Vs CCR5 AND HVI-1

04.08.2010

Des1 "in vitro" and CCR5" in vivo"

GeneCard: CCR5 chemokine (C-C motif) receptor 5 (GC03P046386; Chromosome 3:46,386,637-46,392,695)

The following 19 lines in the GeneCard text contribute to matching your query:
- GENE: CCR5 | chemokine (C-C motif) receptor 5
- ALIASES: C-C chemokine receptor 5 (EG)| CCCKR5 (EG)| CCR5 chemokine receptor (EG)| chemokine (C-C) receptor 5 (EG)| chemokine receptor CCR5 (EG)| chemr13 (EG)| chemokine (C-C motif) receptor 5 (GDB)| CD195 (HGNC)| CD195 (EG)| CKR-5 (HGNC)| CKR-5 (GDB)| CKR-5 (EG)| CKR5 (HGNC)| CKR5 (GDB)| CKR5 (EG)| CC-CKR-5 (HGNC)| CC-CKR-5 (SP)| CC-CKR-5 (GDB)| CC-CKR-5 (EG)| C-C CKR-5 (SP)| CCR-5 (SP)| CD195 antigen (SP)| CHEMR13 (SP)| HIV-1 fusion coreceptor (SP)| C-C chemokine receptor type 5 (SP)| C-C chemokine receptor type 5 (EG)| CMKBR5 (SP)| CMKBR5 (GDB)| CMKBR5 (EG)
- MOUSE HOMOLOG: Ccr5 (on chromosome 9, 72.00 cM) Aug 18 2007 | gbaccs: AF019772 AF022990 AK141906 AK154595 AK155628 AK155632 AK155867 AK170303 BC103574 BC103586 BC103587 BC105643 D83648 U47036 U68565 U83327 X94151 | alleles:id=MGI:3613371;symbol=Ccr5;category=Targeted (knock-out);phenotypes=[ptid=MP:0005385;ptdesc="cardiovascular system phenotype",ptid=MP:0005387;ptdesc="immune system phenotype"] && id=MGI:2429994;symbol=Ccr5;category=Targeted (knock-out);phenotypes=[] && id=MGI:1861911;symbol=Ccr5;category=Targeted (knock-out);phenotypes=[ptid=MP:0005387;ptdesc="immune system phenotype"] && id=MGI:3522335;symbol=Ccr5;category=Targeted (knock-out);phenotypes=[ptid=MP:0005387;ptdesc="immune system phenotype",ptid=MP:0005397;ptdesc="hematopoietic system phenotype"] && id=MGI:3654119;symbol=Ccr5;category=Targeted (knock-out);phenotypes=[ptid=MP:0005381;ptdesc="digestive/alimentary phenotype",ptid=MP:0005386;ptdesc="behavior/neurological phenotype",ptid=MP:0005387;ptdesc="immune system phenotype",ptid=MP:0005397;ptdesc="hematopoietic system phenotype"]
- SWISSPROT: GENE: CCR5
                       POLYMORPHISM: Variations in CCR5 are associated with resistance or susceptibility to immunodeficiency virus type 1 (resistance or susceptibility to HIV-1) [MIM:609423]. Variations in CCR5 gene also influence the rate of progression to AIDS after infection.
                       POLYMORPHISM: Ser-60 variant, a naturally occurring mutation in a conserved residue in the first intracellular domain of CCR5, results in reduced amounts of the protein in the membrane and consequently may be associated with reduced susceptibility to infection by microbes that depend on these molecules as their receptors.
                       POLYMORPHISM: Variations in CCR5 are associated with susceptibility to West Nile virus (WNV) infection [MIM:610379].
                       WEB RESOURCE: NAME=Wikipedia CCR5 receptor entry; URL="http://en.wikipedia.org/wiki/CCR5".
- HGMD: 1230510 | HGMD entry for CCR5 | mutations
- UNIGENE: Hs.450802 | Chemokine (C-C motif) receptor 5 | CCR5 | BC038398 . . .
- LITERATURE: Relative importance of CCR5 and antineutrophil cytoplasmic antibodies in patientswith Wegener's granulomatosis. . . .
- GENATLAS: biochem: chemokine CC,beta,receptor 5,expressed in lymphoid organs and cells,with multiple transcripts with 5' end heterogeneity and dual promoter usage,mediating macrophage-tropic strains of HIV-1 entry in CD4+ cells with a reduced risk of AIDS lymphoma in patients with the CCR5-delta 32 mutation,G protein coupled receptor superfamily | disease:
- ENTREZGENE: chr=3 | contig= | cytoLoc=3p21.31 | dbXrefs=HGNC:1606,MIM:601373,Ensembl:ENSG00000160791,HPRD:03223 | egHugo= | egId=1234 | end=46392695 | geneName=chemokine (C-C motif) receptor 5 | genomicNucAcc=AC098613.2 AF031237.1 AF009962.1 U83326.1 AF052539.1 AF161909.1 AF161910.1 AF161911.1 AF161912.1 AF161913.1 AF161914.1 AF161915.1 AF161916.1 AF161917.1 AF161918.1 AF161919.1 AF161920.1 AF161921.1 AF056020.1 AY221093.1 AY463213.1 AY463214.1 AY463215.1 AY744141.1 AY874119.1 AY874120.1 AY874121.1 DQ217934.1 AB182984.1 AB182988.1 AB182990.1 X91492.1 AX256200.1 AX705068.1 CH471055.1 NT_113884.1 AC_000046.1 NC_000003.10 NT_022517.17 NW_921651.1 | go=GO:0016020 GO:0001584 GO:0009897 GO:0015026 GO:0005737 GO:0005887 GO:0005515 GO:0016021 GO:0006935 GO:0005886 GO:0007186 GO:0004435 GO:0007165 GO:0004872 GO:0016493 GO:0007267 GO:0006968 GO:0006954 GO:0005768 GO:0003779 GO:0006955 GO:0007204 | protAcc=A0A502 AAB94735.1 AAC23944.1 AAC51797.1 AAD18131.1 AAD47666.1 AAD47667.1 AAD47668.1 AAD47669.1 AAD47670.1 AAD47671.1 AAD47672.1 AAD47673.1 AAD47674.1 AAD47675.1 AAD47676.1 AAD47677.1 AAD47678.1 AAF65579.1 AAO65971.1 AAS19312.1 AAS19313.1 AAS19314.1 AAW62445.1 AAW82037.1 AAW82038.1 AAW82039.1 ABB01004.1 BAD83805.1 BAD83807.1 BAD83808.1 CAA62796.1 CAC94550.1 CAD88097.1 EAW64763.1 EAW64764.1 O14694 P51681 Q38L21 Q3L3Q6 Q5EKM8 Q5EKM9 Q5EKN0 Q5KSY4 Q5KSY5 Q5QIN9 Q5QIP0 Q5QIP1 Q9P1T4 Q9P1T8 Q9UBJ7 Q9UBT9 Q9UN23 Q9UN24 Q9UN25 Q9UN26 Q9UN27 Q9UN28 AAB65700.1 AAB65701.1 AAB65702.1 AAB65703.1 AAB65704.1 AAB65705.1 AAB65706.1 AAB65707.1 AAB65708.1 AAB65709.1 AAB65710.1 AAB65711.1 AAB65712.1 AAB65713.1 AAB65714.1 AAB65715.1 AAB65716.1 AAB65717.1 AAB65718.1 AAB65719.1 AAB65720.1 AAB65721.1 AAB65722.1 AAB65723.1 AAB65724.1 AAB65725.1 AAB65726.1 AAB65727.1 AAB65728.1 AAB65729.1 AAB65730.1 AAB65731.1 AAB65732.1 AAB65733.1 AAB65734.1 AAB65735.1 AAB65736.1 AAB65737.1 AAH38398.1 AAC50598.1 AAB17071.1 XP_001125981.1 NP_000570.1 | proteinAliases=C-C chemokine receptor 5|C-C chemokine receptor type 5|CCR5 chemokine receptor|chemokine (C-C) receptor 5|chemokine receptor CCR5|chemr13 | refseq=NM_000579.2(REVIEWED) | rnaNucAcc=AF011500.1 AF011501.1 AF011502.1 AF011503.1 AF011504.1 AF011505.1 AF011506.1 AF011507.1 AF011508.1 AF011509.1 AF011510.1 AF011511.1 AF011512.1 AF011513.1 AF011514.1 AF011515.1 AF011516.1 AF011517.1 AF011518.1 AF011519.1 AF011520.1 AF011521.1 AF011522.1 AF011523.1 AF011524.1 AF011525.1 AF011526.1 AF011527.1 AF011528.1 AF011529.1 AF011530.1 AF011531.1 AF011532.1 AF011533.1 AF011534.1 AF011535.1 AF011536.1 AF011537.1 BC038398.1 DA818906.1 U54994.1 U57840.1 XM_001125981.1 NM_000579.2 | start=46386637 | status=O | symbol=CCR5 | synonyms=CC-CKR-5 CCCKR5 CD195 CKR-5 CKR5 CMKBR5 | type=protein-coding
- HGNC: accs= | aliases=CKR-5, CC-CKR-5, CKR5, CD195 | dateApproved=15/05/1996 | dateModified=22/02/2006 | dateNameChanged= | description=chemokine (C-C motif) receptor 5 | egCuratedId= | egMappedId=1234 | enzymeIds= | gdbId=1230510 | geneFamName=CCR, CD | hgnc=1606 | loc=3p21 | mgdId= | omimId=601373 | prevNames= | prevSymbols=CMKBR5 | pubmedIds=8639485 | refseqId=NM_000579 | refseqMappedId=NM_000579 | status=Approved | symbol=CCR5 | uniprotId=P51681
- HomoloGene:HomoloGene: Organism=Hs|Symbol=LOC727797|Location=|Description=similar to C-C chemokine receptor type 5 (C-C CKR-5) (CC-CKR-5) (CCR-5) (CCR5) (HIV-1 fusion coreceptor) (CHEMR13) (CD195 antigen)|Nuc_Similarity=100|Prot_Similarity=100|EntrezGene=727797|GenBank=XM_001125981.1|Protein=XP_001125981.1|HomologeneId=100533|FormatType=new . . .
- ACEVIEW: aceviewSymbol = CCR5 | acc=U54994;quality=1,acc=U57840;quality=1,acc=AF011536;quality=2,acc=AI417775;quality=2,acc=AF011528;quality=2,acc=AF011506;quality=2,acc=AF011523;quality=2,acc=AF011512;quality=2,acc=AF011524;quality=2,acc=AF011521;quality=2,acc=AF011527;quality=2,acc=AF011508;quality=2,acc=AF011518;quality=2,acc=AW016034;quality=2,acc=AF011531;quality=2,acc=AF011517;quality=2,acc=AF011501;quality=2,acc=AF011533;quality=2,acc=AF011516;quality=2,acc=BQ184010;quality=2,acc=AF011519;quality=2,acc=AF011503;quality=2,acc=AF011507;quality=2,acc=AA361339;quality=2,acc=AF011515;quality=2,acc=AA287788;quality=2,acc=AF011505;quality=2,acc=AF011509;quality=2,acc=AF011520;quality=2,acc=AF011532;quality=2,acc=AF011526;quality=2,acc=AF011534;quality=2,acc=BC038398;quality=2,acc=AF011513;quality=2,acc=AF011529;quality=2,acc=AF011522;quality=2,acc=NM_000579;quality=2,acc=AF011510;quality=2,acc=AF011530;quality=2,acc=AF011504;quality=2,acc=AF011537;quality=2,acc=AF011511;quality=2,acc=AF011525;quality=2,acc=AF011514;quality=2,acc=BX482273;quality=2,acc=AI948825;quality=2,acc=BI764263;quality=2,acc=AF011535;quality=2,acc=BX481558;quality=2,acc=AF011500;quality=2,acc=AF011502;quality=2,acc=BF115566;quality=3,acc=CB046734;quality=3,acc=BF913031;quality=3,acc=CD703001;quality=4,acc=BU429647;quality=6,acc=CB046735;quality=8 || aceviewSymbol = CCR5.1 | acc=U57840;quality=1,acc=U54994;quality=1,acc=AA287788;quality=2,acc=AF011535;quality=2,acc=AF011508;quality=2,acc=AF011527;quality=2,acc=AF011504;quality=2,acc=AF011501;quality=2,acc=AF011534;quality=2,acc=NM_000579;quality=2,acc=AF011502;quality=2,acc=AA361339;quality=2,acc=AF011532;quality=2,acc=BX481558;quality=2,acc=AF011526;quality=2,acc=AF011529;quality=2,acc=AF011524;quality=2,acc=AF011533;quality=2,acc=AF011503;quality=2,acc=AF011509;quality=2,acc=AF011522;quality=2,acc=AF011530;quality=2,acc=AF011528;quality=2,acc=AF011516;quality=2,acc=AF011517;quality=2,acc=AF011505;quality=2,acc=AF011510;quality=2,acc=AF011500;quality=2,acc=AW016034;quality=2,acc=AF011520;quality=2,acc=AF011519;quality=2,acc=AF011523;quality=2,acc=AF011511;quality=2,acc=BX482273;quality=2,acc=AF011537;quality=2,acc=AF011506;quality=2,acc=AF011515;quality=2,acc=AI417775;quality=2,acc=AF011521;quality=2,acc=AF011514;quality=2,acc=AF011512;quality=2,acc=AF011536;quality=2,acc=AI948825;quality=2,acc=AF011531;quality=2,acc=BI764263;quality=2,acc=AF011507;quality=2,acc=AF011518;quality=2,acc=AF011525;quality=2,acc=BC038398;quality=2,acc=AF011513;quality=2,acc=BF913031;quality=3,acc=BF115566;quality=3,acc=CB046734;quality=3,acc=CD703001;quality=4,acc=BU429647;quality=6,acc=CB046735;quality=8
- GAD: geneSymbol=CCR5
- GDPINFO: geneSymbol=CCR5 | numDocs=145
- ECGENE: geneSymbol=CCR5
- EXPOLDB: geneSymbol=CCR5
- CST: products: | pathways: | phosphosite: protein=CCR5;psdbmolid=1943
- ABCAM: protein=CCR5;tid=8517
- GENETEX: catalog=GTX30616 | descr=Rabbit polyclonal antibody to CCR 5 (C-C Chemokine Receptor 5) | productId=31723 || catalog=GTX41653 | descr=Rabbit polyclonal to CCR5 | productId=29035 || catalog=GTX11466 | descr=Rat monoclonal [HEK / 1 / 85a] to CCR5 ( FITC ) | productId=23470 || catalog=GTX11464 | descr=Rat monoclonal [HEK / 1 / 85a] to CCR5 | productId=23468 || catalog=GTX10397 | descr=Mouse monoclonal [45523.111] to CCR5 | productId=16115 || catalog=GTX27346 | descr=Rabbit polyclonal to CCR5 | productId=5267 || catalog=GTX21673 | descr=Goat polyclonal to CCR5 | productId=3067