Le blog de rodolfo

Antioxidant Action of Vitamin-C

Par BRUNETTI

Oxidative stress/Hypoxia is induced by a wide range of environmental factors including UV stress, pathogen invasion (hypersensitive reaction), oxygen shortage, etc. Generation of ROS (Reactive Oxygen Species) is characteristic feature of such stress conditions....

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Pathogenesis of Multiple Sclerosis

Par BRUNETTI

MS (Multiple Sclerosis) is an inflammatory and demyelinating disease of the CNS (Central Nervous System). MS is classified according to its clinical course into several categories: benign, RR (Relapsing-Remitting, the most common variant), PR (Progressive-Relapsing),...

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LinkedIn

Par BRUNETTI

Cuando publicas un contenido en LinkedInpasa por un proceso de supervisión mixto (máquina/humano) de lo más curioso: 1) Clasificación LinkedIn clasifica de forma automática cada imagen, texto, artículo o vídeo en tres posibles grupos: “OK” (“clear”) Baja...

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Ascorbic acid

Par BRUNETTI

Vitamin C preferentially kills cancer stem cells in hepatocellular carcinoma via SVCT-2 Hongwei Lv , Changzheng Wang , […] Hongyang Wang npj Precision Oncology volume 2, Article number: 1 (2018)

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Molecular Mechanisms of Cancer, part II

Par BRUNETTI

Within a normal tissue, multiple anti-proliferative signals operate to maintain cellular quiescence and tissue homeostasis. Incipient cancer cells evade these anti-proliferative signals in order to prosper. Cancer cells also switch to different types,...

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Fibrosis quística

Par BRUNETTI

Regulación dependiente de CFTR de los canales iónicos en el epitelio de las vías respiratorias (norma y CF) Receptor IP3 , región extracelular ATP , ENaC , luz del retículo endoplásmico Ca ('2+) , DAG , YAP1 (YAp65) , región extracelular K (' +) , proteína...

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Fibrosis (FIBROSIS QUISTICA) " THE PROTEIN IS IN YOUNG HUMAN PLASMA IN SUFFICIENT AMOUNT "CFTR",

Par BRUNETTI

CFTR (Cystic Fibrosis Transmembrane Conductance Regulator) is a Protein Coding gene. Diseases associated with CFTR include Cystic Fibrosis and Vas Deferens, Congenital Bilateral Aplasia Of . Among its related pathways are Bacterial infections in CF airways...

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third part. Molecular mechanisms and signaling pathways that are activated with blood or plasma from young donors

Par BRUNETTI

References Eupafolin suppresses prostate cancer by targeting phosphatidylinositol 3-kinase-mediated Akt signaling. Ankrd2/ARPP is a novel Akt2 specific substrate and regulates myogenic differentiation upon cellular exposure to H(2)O(2). Contribution of...

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Second part. Molecular mechanisms and signaling pathways that are activated with blood or plasma from young donors

Par BRUNETTI

Akt inhibits apoptosis by phosphorylating the BADcomponent of the BAD/BclXL complex. Phosphorylated BAD binds to 14-3-3 causing dissociation of the BAD/BclXLcomplex and allowing cell survival. Akt activates IKK, which ultimately leads to NF-KappaB activation...

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Molecular mechanisms and signaling pathways that are activated with blood or plasma from young donors

Par BRUNETTI

Akt Signaling Akt is an evolutionarily conserved serine/threonine kinase involved in a wide variety of cellular functions, including proliferation, cell survival, differentiation, glucose mobilization, homeostasis, cell migration, and apoptosis. Three...

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