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Information scientifique avancée

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Vero cell

The Vero cells (of the Esperanto: " sees rda r in or " and " vero " meaning "green kidney" and "right", respectively) belong to a cell line used in cell cultures  The lineage Vero was isolated from the epithelial cells of the kidney of an African green monkey ( Chlorocebus sp .; formerly called Cercopithecus aethiops ). The Vero cell lineage is continuous and aneuploidic , meaning that it can replicate through many replication cycles without aging And has an abnormal number of chromosomes . It allows the production of vaccines against viral diseases. It is also used in scientific studies of microbiology, cell and molecular biology.

Vero cells are used for many purposes, including:

 

Monitoring the Escherichia coli toxin , called, because of its discovery in this cell lineage as "Vero toxin", later it will receive the name of " Shiga-like toxin " due to its similarity to Shiga toxin isolated from Shigella dysenteriae

Use as host cells for virus growth (it is susceptible to a high range of viruses such as polio , rubella, arboviruses and reoviruses ,for example: in pharmaceutical research viral replication is measured in the absence and presence of the drug, in epidemiology the presence of rabies virus can be observed , or in research the growth of stored viruses is seen

Cell serves as a substrate for the production of viral vaccines, for example Cepalvan A / H1N1 / 2009

and rabies vaccines Vero cells 

Use as host cells for eukaryotic parasites , especially Trypanosomatida

 

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