Information scientifique avancée
Alzheimer, Parkinson, causas múltiples, enfermedades múltiples, hay un problema muy serio a nivel investigaciones, varios laboratorios se disputan tratamiento de la demencia senil, para evitar los depósitos de la TAU. Los grupos de investigación de todo...
PENSIONISTAS Mensaje Sr Presidente El Gobierno de España debe llevar al Parlamento el aumento de las Pensiones de forma Urgente, puesto que el presidente se había comprometido. De la torta que es el dinero de los presupuestos generales, se puede aumentar...
El ácido Elágico es uno de los descubrimientos de salud más importantes de esta década y ésta relacionado directamente con la prevención y tratamiento en métodos alternativos contra el cáncer. La Sociedad Americana de Cáncer comentó que el ácido Elágico:...
Scientists clearly demonstrate rejuvenating in different organs, brain, heart, muscle, bone, pancreas, liver ... (Tony Wyss-Coray et al., 2015, Saul Villeda et al., 2011, 2014, Katsimpardi et al., 2014, Bath et al. 2015, Conboy et al 2005, Sinka et al...
The ectopic expression of transcription factors OCT4, SOX2, KLF4, and cMYC (OSKM) enables reprogramming of adult differentiated cells into pluripotent cells, known as induced pluripotent stem cells (iPSCs), that are functionally equivalent to embryonic...
The Notch signaling pathway is a highly conserved cell signaling system present in most multicellular organisms. Notch signaling plays a pivotal role in the regulation of many fundamental cellular processes such as proliferation, stem cell maintenance...
Autologous plasma is somewhat effective in accelerating healing or regenerating local soft tissue or bone, until 25 or 30 years of age, older has much uncertainty because their levels of growth factors are greatly diminished, anyway an injury either increases...
SIRT6 SIRT6 is a nuclear sirtuin and has roles that differ from those of SIRT1. SIRT6-knockout mice exhibit aging-like phenotypes, such as lymphopenia, loss of subcutaneous fat and severe hypoglycemia, which lead to their death by 4-5 weeks (Mostoslavsky...
Roles in metabolism pathways and metabolic diseases SIRT1 regulates various metabolic processes that allow the cell to adapt to nutrient stress and has a pivotal role in aging-related metabolic diseases. In response to fasting, SIRT1 modulates gluconeogenesis...
Roles in cancer The role of SIRT1 in tumor progression is controversial, as SIRT1 might have dual functions as an oncogene and tumor suppressor. The initial evidence that SIRT1 might function as an oncogene was the observation that it deacetylates lysine...
REFERENCES___________________________________________________________________________________ 1. Burke SN, Barnes CA. Neural plasticity in the ageing brain. Nat Rev Neurosci. 2006;7(1):30-40. 2. Conboy IM, Conboy MJ, Wagers AJ, Girma ER, Weissman IL ,...
Sox10 labeling in metastatic breast carcinomas. Nelson ER 1, Sharma R 1, Argani P 2, Cimino-Mathews A 3. Author information Abstract Sox10 labeling by immunohistochemistry has been primarily reported in tumors of neural crest origin, such as nerve sheath...
Wednesday, October 17, 2018 11 a.m. UK (BST), 12 noon Central Europe (CEST) Duration: 1 hour This webinar includes a rebroadcast of the presentations from a previous event, followed by a new live Q&A. There is growing recognition that the nervous and...
Wilkinson D (1997). Wilkinson D (1997). "Cofactors provide the entry keys. HIV-1". Curr. "Cofactores ofrecer las claves de entrada. VIH-1". Curr. Biol. 6 (9): 1051–3. doi : 10.1016/S0960-9822(02)70661-1 . PMID 8805353 . Biol. 6 (9): 1051-3. doi : 10.1016/S0960-9822...
Two other genes linked to early-onset familial Alzheimer Disease are those encoding Presenilin 1 (chromosome 14) and Presenilin 2 (chromosome 1). PS1 and PS2 are structurally similar integral membrane proteins with eight transmembrane domains and are...
El virus del Zika (ZIKV) es un virus del género Flavivirus , de la familia Flaviviridae, grupo IV del orden sin clasificar que se transmite por la picadura de mosquitos vectores del género Aedes . En los seres humanos produce la fiebre del Zika o enfermedad...
This gene encodes catalase, a key antioxidant enzyme in the bodies defense against oxidative stress. Catalase is a heme enzyme that is present in the peroxisome of nearly all aerobic cells. Catalase converts the reactive oxygen species hydrogen peroxide...
CCR5-Δ32 es una mutación de deleción de un gen que tiene un impacto específico sobre la función de células T . CCR5-Δ32 is widely dispersed throughout Northern Europe and in those of Northern European descent . CCR5-Δ32 está muy disperso por todo el norte...
La inmunoglobulina A (IgA) es la clase predominante de anticuerpo en las secreciones de las mucosas del organismo como saliva, lágrimas, calostro, leche y secreciones respiratorias, gastrointestinales y genitourinarias. En sangre, se encuentra como una...
Muchos virus han desarrollado mecanismos para resistir la actividad del interferón. Evitan la respuesta de IFN bloqueando los eventos de señalización descendente que ocurren después de que la citocina se une a su receptor, evitando una mayor producción...
Todos los interferones comparten varios efectos comunes: son agentes antivirales y modulan las funciones del sistema inmunológico. Se ha demostrado experimentalmente que la administración de IFN de tipo I inhibe el crecimiento tumoral en animales, pero...
Un inicio de vanguardia está trabajando en un tratamiento para enfermedades neurodegenerativas como el Parkinson y el Alzheimer al alterar la concentración de proteínas plasmáticas en los pacientes. Este trabajo se basó en investigaciones previas de la...
Alzheimer disease (AD) is a progressive neurodegenerative disorder caused by an increase in amyloid metabolism. Mutations in some of the components of the amyloid pathway, such as the amyloid precursor protein ( APP ), ApoE , Presenilin-1 and PS2 ( PS1...
1. COVID-19 is NOT transmitted asymptomatically people can transmit the disease to other people and insisted that only people who show symptoms are truly contagious. “The virus is not transmitted asymptomatically. Only the sick transmit it to other people....
PHILADELPHIA — Many Americans have shelled out hundreds of dollars for biological age tests promising to reveal whether their bodies are aging faster or slower than their actual years. These methylation-based “aging clocks” have become the gold standard...
